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Production of Functionally Active and Immunogenic Non-Glycosylated Protective Antigen from Bacillus anthracis in Nicotiana benthamiana by Co-Expression with Peptide-N-Glycosidase F (PNGase F) of Flavobacterium meningosepticum
Bacillus anthracis has long been considered a potential biological warfare agent, and therefore, there is a need for a safe, low-cost and highly efficient anthrax vaccine with demonstrated long-term stability for mass vaccination in case of an emergency. Many efforts have been made towards developin...
Autores principales: | Mamedov, Tarlan, Chichester, Jessica A., Jones, R. Mark, Ghosh, Ananya, Coffin, Megan V., Herschbach, Kristina, Prokhnevsky, Alexey I., Streatfield, Stephen J., Yusibov, Vidadi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839623/ https://www.ncbi.nlm.nih.gov/pubmed/27101370 http://dx.doi.org/10.1371/journal.pone.0153956 |
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