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Sustained Effect of Hyaluronic Acid in Subcutaneous Administration to the Cochlear Spiral Ganglion

The spatiotemporal distribution of drugs in the inner ear cannot be precisely evaluated because of its small area and complex structure. In the present study, we used hyaluronic acid (HA)-dispersed luciferin to image transgenic mice and to determine the effect of HA on controlled drug delivery to th...

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Detalles Bibliográficos
Autores principales: Inagaki, Yozo, Fujioka, Masato, Kanzaki, Sho, Watanabe, Kotaro, Oishi, Naoki, Itakura, Go, Yasuda, Akimasa, Shibata, Shinsuke, Nakamura, Masaya, Okano, Hirotaka James, Okano, Hideyuki, Ogawa, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839654/
https://www.ncbi.nlm.nih.gov/pubmed/27099926
http://dx.doi.org/10.1371/journal.pone.0153957