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Sustained Effect of Hyaluronic Acid in Subcutaneous Administration to the Cochlear Spiral Ganglion
The spatiotemporal distribution of drugs in the inner ear cannot be precisely evaluated because of its small area and complex structure. In the present study, we used hyaluronic acid (HA)-dispersed luciferin to image transgenic mice and to determine the effect of HA on controlled drug delivery to th...
Autores principales: | Inagaki, Yozo, Fujioka, Masato, Kanzaki, Sho, Watanabe, Kotaro, Oishi, Naoki, Itakura, Go, Yasuda, Akimasa, Shibata, Shinsuke, Nakamura, Masaya, Okano, Hirotaka James, Okano, Hideyuki, Ogawa, Kaoru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839654/ https://www.ncbi.nlm.nih.gov/pubmed/27099926 http://dx.doi.org/10.1371/journal.pone.0153957 |
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