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In Vitro Polarization of Colonoids to Create an Intestinal Stem Cell Compartment
The polarity of proliferative and differentiated cellular compartments of colonic crypts is believed to be specified by gradients of key mitogens and morphogens. Indirect evidence demonstrates a tight correlation between Wnt- pathway activity and the basal-luminal patterning; however, to date there...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839657/ https://www.ncbi.nlm.nih.gov/pubmed/27100890 http://dx.doi.org/10.1371/journal.pone.0153795 |