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In Vitro Polarization of Colonoids to Create an Intestinal Stem Cell Compartment

The polarity of proliferative and differentiated cellular compartments of colonic crypts is believed to be specified by gradients of key mitogens and morphogens. Indirect evidence demonstrates a tight correlation between Wnt- pathway activity and the basal-luminal patterning; however, to date there...

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Detalles Bibliográficos
Autores principales: Attayek, Peter J., Ahmad, Asad A., Wang, Yuli, Williamson, Ian, Sims, Christopher E., Magness, Scott T., Allbritton, Nancy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839657/
https://www.ncbi.nlm.nih.gov/pubmed/27100890
http://dx.doi.org/10.1371/journal.pone.0153795