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Antigenic Fingerprinting following Primary RSV Infection in Young Children Identifies Novel Antigenic Sites and Reveals Unlinked Evolution of Human Antibody Repertoires to Fusion and Attachment Glycoproteins

Respiratory Syncytial Virus (RSV) is the major cause of pneumonia among infants. Here we elucidated the antibody repertoire following primary RSV infection and traced its evolution through adolescence and adulthood. Whole genome-fragment phage display libraries (GFPDL) expressing linear and conforma...

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Detalles Bibliográficos
Autores principales: Fuentes, Sandra, Coyle, Elizabeth M., Beeler, Judy, Golding, Hana, Khurana, Surender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839671/
https://www.ncbi.nlm.nih.gov/pubmed/27100289
http://dx.doi.org/10.1371/journal.ppat.1005554