PBRM1 Regulates the Expression of Genes Involved in Metabolism and Cell Adhesion in Renal Clear Cell Carcinoma

Polybromo-1 (PBRM1) is a component of the PBAF (Polybromo-associated-BRG1- or BRM-associated factors) chromatin remodeling complex and is the second most frequently mutated gene in clear-cell renal cell Carcinoma (ccRCC). Mutation of PBRM1 is believed to be an early event in carcinogenesis, however...

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Detalles Bibliográficos
Autores principales: Chowdhury, Basudev, Porter, Elizabeth G., Stewart, Jane C., Ferreira, Christina R., Schipma, Matthew J., Dykhuizen, Emily C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839679/
https://www.ncbi.nlm.nih.gov/pubmed/27100670
http://dx.doi.org/10.1371/journal.pone.0153718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839679/
https://www.ncbi.nlm.nih.gov/pubmed/27100670
http://dx.doi.org/10.1371/journal.pone.0153718

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