Molecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor Internalisation

The glucagon-like peptide receptor (GLP-1R), which is a G-protein coupled receptor (GPCR), signals through both Gαs and Gαq coupled pathways and ERK phosphorylation to stimulate insulin secretion. The aim of this study was to determine molecular details of the effect of small molecule agonists, comp...

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Detalles Bibliográficos
Autores principales: Thompson, Aiysha, Stephens, Jeffrey W., Bain, Stephen C., Kanamarlapudi, Venkateswarlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839733/
https://www.ncbi.nlm.nih.gov/pubmed/27100083
http://dx.doi.org/10.1371/journal.pone.0154229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839733/
https://www.ncbi.nlm.nih.gov/pubmed/27100083
http://dx.doi.org/10.1371/journal.pone.0154229

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