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SMOC Binds to Pro-EGF, but Does Not Induce Erk Phosphorylation via the EGFR

In an attempt to identify the cell-associated protein(s) through which SMOC (Secreted Modular Calcium binding protein) induces mitogen-activated protein kinase (MAPK) signaling, the epidermal growth factor receptor (EGFR) became a candidate. However, although in 32D/EGFR cells, the EGFR was phosphor...

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Detalles Bibliográficos
Autores principales: Thomas, J. Terrig, Chhuy-Hy, Lina, Andrykovich, Kristin R., Moos, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839742/
https://www.ncbi.nlm.nih.gov/pubmed/27101391
http://dx.doi.org/10.1371/journal.pone.0154294