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MicroRNA Expression Signatures Associated With BRAF-Mutated Versus KRAS-Mutated Colorectal Cancers

BRAF and KRAS genes are known to play a similar role in the activation of RAS-RAF-MEK-ERK signaling pathway in colorectal tumorigenesis. However, BRAF-mutated colorectal cancers (CRCs) have distinct clinicopathologic characteristics different from those of the KRAS mutated ones as in comparison the...

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Detalles Bibliográficos
Autores principales: Choi, Yong Won, Song, Young Soo, Lee, Hyunwoo, Yi, Kijong, Kim, Young-Bae, Suh, Kwang Wook, Lee, Dakeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839821/
https://www.ncbi.nlm.nih.gov/pubmed/27082577
http://dx.doi.org/10.1097/MD.0000000000003321