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Elevated Serum Leptin Levels are Associated With an Increased Risk of Sentinel Lymph Node Metastasis in Cutaneous Melanoma

The metabolic hormone leptin has been implicated in the pathogenesis of various malignancies and may contribute to the high rate of cancer in obese individuals. We reported that leptin and its receptor are expressed by melanoma tumors and cell lines, and that leptin stimulates proliferation of cultu...

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Detalles Bibliográficos
Autores principales: Oba, Junna, Wei, Wei, Gershenwald, Jeffrey E., Johnson, Marcella M., Wyatt, Cynthia M., Ellerhorst, Julie A., Grimm, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839916/
https://www.ncbi.nlm.nih.gov/pubmed/26986135
http://dx.doi.org/10.1097/MD.0000000000003073