Increased APRIL Expression Induces IgA1 Aberrant Glycosylation in IgA Nephropathy

Aberrant glycosylated IgA1 molecules, mainly galactose-deficient IgA1 (Gd-IgA1), are important causal factors in IgA nephropathy; however, the underlying mechanism for the production of aberrantly glycosylated IgA1 is unknown. A recent genome-wide association study identified a novel IgAN susceptibi...

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Detalles Bibliográficos
Autores principales: Zhai, Ya-Ling, Zhu, Li, Shi, Su-Fang, Liu, Li-Jun, Lv, Ji-Cheng, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
5200
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839931/
https://www.ncbi.nlm.nih.gov/pubmed/26986150
http://dx.doi.org/10.1097/MD.0000000000003099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839931/
https://www.ncbi.nlm.nih.gov/pubmed/26986150
http://dx.doi.org/10.1097/MD.0000000000003099

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