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Mouse anti-RANKL antibody delays oral wound healing and increases TRAP-positive mononuclear cells in bone marrow

OBJECTIVES: Denosumab, a human monoclonal antibody (mAb) that neutralizes receptor activator for nuclear factor κB ligand (RANKL), is associated with osteonecrosis of the jaw. However, the effect of denosumab on oral wounds is unclear. The aim was to determine the effect of anti-RANKL mAb on oral wo...

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Detalles Bibliográficos
Autores principales: Kuroshima, Shinichiro, Al-Salihi, Zeina, Yamashita, Junro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840226/
https://www.ncbi.nlm.nih.gov/pubmed/26254598
http://dx.doi.org/10.1007/s00784-015-1550-0