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Intranasal Dopamine Reduces In Vivo [(123)I]FP-CIT Binding to Striatal Dopamine Transporter: Correlation with Behavioral Changes and Evidence for Pavlovian Conditioned Dopamine Response

Purpose: Dopamine (DA), which does not cross the blood-brain barrier, has central and behavioral effects when administered via the nasal route. Neither the mechanisms of central action of intranasal dopamine (IN-DA), nor its mechanisms of diffusion and transport into the brain are well understood. W...

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Detalles Bibliográficos
Autores principales: de Souza Silva, Maria A., Mattern, Claudia, Decheva, Cvetana, Huston, Joseph P., Sadile, Adolfo G., Beu, Markus, Müller, H.-W., Nikolaus, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840254/
https://www.ncbi.nlm.nih.gov/pubmed/27148001
http://dx.doi.org/10.3389/fnbeh.2016.00080