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Genotoxicity of flubendazole and its metabolites in vitro and the impact of a new formulation on in vivo aneugenicity
The anti-parasitic benzimidazole flubendazole has been used for many years to treat intestinal infections in humans and animals. Previous genotoxicity studies have shown that the compound is not a bacterial mutagen and a bone marrow micronucleus test, using a formulation that limited systemic absorp...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840262/ https://www.ncbi.nlm.nih.gov/pubmed/26443851 http://dx.doi.org/10.1093/mutage/gev070 |