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Genotoxicity of flubendazole and its metabolites in vitro and the impact of a new formulation on in vivo aneugenicity

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The anti-parasitic benzimidazole flubendazole has been used for many years to treat intestinal infections in humans and animals. Previous genotoxicity studies have shown that the compound is not a bacterial mutagen and a bone marrow micronucleus test, using a formulation that limited systemic absorp...

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Detalles Bibliográficos
Autores principales:	Tweats, David J., Johnson, George E., Scandale, Ivan, Whitwell, James, Evans, Dean B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Special Issue: Quantitative Genetic Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840262/ https://www.ncbi.nlm.nih.gov/pubmed/26443851 http://dx.doi.org/10.1093/mutage/gev070

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