Breast Cancer Heterogeneity Examined by High-Sensitivity Quantification of PIK3CA, KRAS, HRAS, and BRAF Mutations in Normal Breast and Ductal Carcinomas()()

Mutant cancer subpopulations have the potential to derail durable patient responses to molecularly targeted cancer therapeutics, yet the prevalence and size of such subpopulations are largely unexplored. We employed the sensitive and quantitative Allele-specific Competitive Blocker PCR approach to c...

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Detalles Bibliográficos
Autores principales: Myers, Meagan B., Banda, Malathi, McKim, Karen L., Wang, Yiying, Powell, Michael J., Parsons, Barbara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840288/
https://www.ncbi.nlm.nih.gov/pubmed/27108388
http://dx.doi.org/10.1016/j.neo.2016.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840288/
https://www.ncbi.nlm.nih.gov/pubmed/27108388
http://dx.doi.org/10.1016/j.neo.2016.03.002

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