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p53: out of Africa
Somatic mutations in the tumor suppressor gene p53 occur in more than half of all human cancers. Rare germline mutations result in the Li-Fraumeni cancer family syndrome. In this issue of Genes & Development, Jennis and colleagues (pp. 918–930) use an elegant mouse model to examine the affect of...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840293/ https://www.ncbi.nlm.nih.gov/pubmed/27083994 http://dx.doi.org/10.1101/gad.281733.116 |