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CTCF: making the right connections

The role of the zinc finger protein CTCF in organizing the genome within the nucleus is now well established. Widely separated sites on DNA, occupied by both CTCF and the cohesin complex, make physical contacts that create large loop domains. Additional contacts between loci within those domains, of...

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Detalles Bibliográficos
Autores principales: Ghirlando, Rodolfo, Felsenfeld, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840295/
https://www.ncbi.nlm.nih.gov/pubmed/27083996
http://dx.doi.org/10.1101/gad.277863.116