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CTCF: making the right connections
The role of the zinc finger protein CTCF in organizing the genome within the nucleus is now well established. Widely separated sites on DNA, occupied by both CTCF and the cohesin complex, make physical contacts that create large loop domains. Additional contacts between loci within those domains, of...
Autores principales: | Ghirlando, Rodolfo, Felsenfeld, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840295/ https://www.ncbi.nlm.nih.gov/pubmed/27083996 http://dx.doi.org/10.1101/gad.277863.116 |
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