Cargando…

Collaboration of RAG2 with RAG1-like proteins during the evolution of V(D)J recombination

The recombination-activating gene 1 (RAG1) and RAG2 proteins initiate V(D)J recombination, the process that assembles the B- and T-lymphocyte antigen receptor genes of jawed vertebrates. RAG1 and RAG2 are thought to have arisen from a transposable element, but the origins of this element are not und...

Descripción completa

Detalles Bibliográficos
Autores principales: Carmona, Lina Marcela, Fugmann, Sebastian D., Schatz, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840297/
https://www.ncbi.nlm.nih.gov/pubmed/27056670
http://dx.doi.org/10.1101/gad.278432.116