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Collaboration of RAG2 with RAG1-like proteins during the evolution of V(D)J recombination
The recombination-activating gene 1 (RAG1) and RAG2 proteins initiate V(D)J recombination, the process that assembles the B- and T-lymphocyte antigen receptor genes of jawed vertebrates. RAG1 and RAG2 are thought to have arisen from a transposable element, but the origins of this element are not und...
Autores principales: | Carmona, Lina Marcela, Fugmann, Sebastian D., Schatz, David G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840297/ https://www.ncbi.nlm.nih.gov/pubmed/27056670 http://dx.doi.org/10.1101/gad.278432.116 |
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