GTP-binding of ARL-3 is activated by ARL-13 as a GEF and stabilized by UNC-119

Primary cilia are sensory organelles indispensable for organogenesis and tissue pattern formation. Ciliopathy small GTPase ARLs are proposed as prominent ciliary switches, which when disrupted result in dysfunctional cilia, yet how ARLs are activated remain elusive. Here, we discover a novel small G...

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Detalles Bibliográficos
Autores principales: Zhang, Qing, Li, Yan, Zhang, Yuxia, Torres, Vicente E., Harris, Peter C., Ling, Kun, Hu, Jinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840320/
https://www.ncbi.nlm.nih.gov/pubmed/27102355
http://dx.doi.org/10.1038/srep24534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840320/
https://www.ncbi.nlm.nih.gov/pubmed/27102355
http://dx.doi.org/10.1038/srep24534

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