Constructing and Validating High-Performance MIEC-SVM Models in Virtual Screening for Kinases: A Better Way for Actives Discovery

The MIEC-SVM approach, which combines molecular interaction energy components (MIEC) derived from free energy decomposition and support vector machine (SVM), has been found effective in capturing the energetic patterns of protein-peptide recognition. However, the performance of this approach in iden...

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Detalles Bibliográficos
Autores principales: Sun, Huiyong, Pan, Peichen, Tian, Sheng, Xu, Lei, Kong, Xiaotian, Li, Youyong, Dan Li, Hou, Tingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840416/
https://www.ncbi.nlm.nih.gov/pubmed/27102549
http://dx.doi.org/10.1038/srep24817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840416/
https://www.ncbi.nlm.nih.gov/pubmed/27102549
http://dx.doi.org/10.1038/srep24817

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