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Imperatorin derivative OW1 inhibits the upregulation of TGF-β and MMP-2 in renovascular hypertension-induced cardiac remodeling

Chronic hypertension induces vascular and cardiac remodeling. OW1 is a novel imperatorin derivative that was previously reported to inhibit vascular remodeling and improve kidney function affected by hypertension. In the present study, the effect of OW1 on the cardiac remodeling induced by hypertens...

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Detalles Bibliográficos
Autores principales: ZHOU, NAN, ZHU, YANING, ZHANG, PENG, ZHANG, YU, ZHOU, MINGYAO, WANG, TAO, HE, LANGCHONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840669/
https://www.ncbi.nlm.nih.gov/pubmed/27168797
http://dx.doi.org/10.3892/etm.2016.3172