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Status of hepatic DNA methylome predetermines and modulates the severity of non-alcoholic fatty liver injury in mice
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a major health problem and a leading cause of chronic liver disease in the United States and Western countries. In humans, genetic factors greatly influence individual susceptibility to NAFLD; nonetheless, the effect of inter-individual differe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840954/ https://www.ncbi.nlm.nih.gov/pubmed/27103143 http://dx.doi.org/10.1186/s12864-016-2617-2 |