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microRNA-206 is involved in survival of hypoxia preconditioned mesenchymal stem cells through targeting Pim-1 kinase

BACKGROUND: Overexpression of Pim-1 in stem/progenitor cells stimulated cell cycling and enhanced cardiac regeneration in vivo. We proposed that hypoxic preconditioning could increase survival of bone marrow mesenchymal stem cells (MSCs) via upregulation of Pim-1 and aimed to determine the microRNAs...

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Detalles Bibliográficos
Autores principales: Zhang, You, Lei, Wei, Yan, Weiya, Li, Xizhe, Wang, Xiaolin, Zhao, Zhenao, Hui, Jie, Shen, Zhenya, Yang, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840980/
https://www.ncbi.nlm.nih.gov/pubmed/27103465
http://dx.doi.org/10.1186/s13287-016-0318-z