Chronic subordination stress selectively downregulates the insulin signaling pathway in liver and skeletal muscle but not in adipose tissue of male mice

Chronic stress has been associated with obesity, glucose intolerance, and insulin resistance. We developed a model of chronic psychosocial stress (CPS) in which subordinate mice are vulnerable to obesity and the metabolic-like syndrome while dominant mice exhibit a healthy metabolic phenotype. Here...

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Detalles Bibliográficos
Autores principales: Sanghez, Valentina, Cubuk, Cankut, Sebastián-Leon, Patricia, Carobbio, Stefania, Dopazo, Joaquin, Vidal-Puig, Antonio, Bartolomucci, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Original Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841025/
https://www.ncbi.nlm.nih.gov/pubmed/26946982
http://dx.doi.org/10.3109/10253890.2016.1151491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841025/
https://www.ncbi.nlm.nih.gov/pubmed/26946982
http://dx.doi.org/10.3109/10253890.2016.1151491

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