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Chronic subordination stress selectively downregulates the insulin signaling pathway in liver and skeletal muscle but not in adipose tissue of male mice
Chronic stress has been associated with obesity, glucose intolerance, and insulin resistance. We developed a model of chronic psychosocial stress (CPS) in which subordinate mice are vulnerable to obesity and the metabolic-like syndrome while dominant mice exhibit a healthy metabolic phenotype. Here...
Autores principales: | Sanghez, Valentina, Cubuk, Cankut, Sebastián-Leon, Patricia, Carobbio, Stefania, Dopazo, Joaquin, Vidal-Puig, Antonio, Bartolomucci, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841025/ https://www.ncbi.nlm.nih.gov/pubmed/26946982 http://dx.doi.org/10.3109/10253890.2016.1151491 |
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