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Quantitative methylation analysis reveals distinct association between PAX6 methylation and clinical characteristics with different viral infections in hepatocellular carcinoma

BACKGROUND: Related to genetic alteration, frequent promoter hypermethylation is also a contributing factor in the development of human cancers. Recently, we discovered numerous novel genes that were aberrantly methylated in hepatocellular carcinoma (HCC) by using Infinium HumanMethylation27 BeadChi...

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Detalles Bibliográficos
Autores principales: Shih, Yu-Lueng, Kuo, Chih-Chi, Yan, Ming-De, Lin, Ya-Wen, Hsieh, Chung-Bao, Hsieh, Tsai-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841049/
https://www.ncbi.nlm.nih.gov/pubmed/27110298
http://dx.doi.org/10.1186/s13148-016-0208-3