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Wnt signaling in cancer stem cells and colon cancer metastasis

Overactivation of Wnt signaling is a hallmark of colorectal cancer (CRC). The Wnt pathway is a key regulator of both the early and the later, more invasive, stages of CRC development. In the normal intestine and colon, Wnt signaling controls the homeostasis of intestinal stem cells (ISCs) that fuel,...

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Detalles Bibliográficos
Autores principales: Basu, Sayon, Haase, Gal, Ben-Ze'ev, Avri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841194/
https://www.ncbi.nlm.nih.gov/pubmed/27134739
http://dx.doi.org/10.12688/f1000research.7579.1