Zoledronate upregulates MMP-9 and -13 in rat vascular smooth muscle cells by inducing oxidative stress

BACKGROUND: Bisphosphonates, including zoledronate, target osteoclasts and are widely used in the treatment of osteoporosis and other bone resorption diseases, despite side effects that include damaging the stomach epithelium. Beneficial and adverse effects on other organ systems, including the card...

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Detalles Bibliográficos
Autores principales: Arun, Mehmet Zuhuri, Reel, Buket, Sala-Newby, Graciela B, Bond, Mark, Tsaousi, Aikaterini, Maskell, Perry, Newby, Andrew C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841407/
https://www.ncbi.nlm.nih.gov/pubmed/27143852
http://dx.doi.org/10.2147/DDDT.S103124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841407/
https://www.ncbi.nlm.nih.gov/pubmed/27143852
http://dx.doi.org/10.2147/DDDT.S103124

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