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Development and characterization of self-assembling lecithin-based mixed polymeric micelles containing quercetin in cancer treatment and an in vivo pharmacokinetic study

Quercetin (Que) is known to have biological benefits including an anticancer effect, but low water solubility limits its clinical application. The aim of this study was to develop a lecithin-based mixed polymeric micelle (LMPM) delivery system to improve the solubility and bioavailability of Que. Th...

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Detalles Bibliográficos
Autores principales: Chen, Ling-Chun, Chen, Ying-Chen, Su, Chia-Yu, Hong, Chung-Shu, Ho, Hsiu-O, Sheu, Ming-Thau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841422/
https://www.ncbi.nlm.nih.gov/pubmed/27143878
http://dx.doi.org/10.2147/IJN.S103681