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Development and characterization of self-assembling lecithin-based mixed polymeric micelles containing quercetin in cancer treatment and an in vivo pharmacokinetic study
Quercetin (Que) is known to have biological benefits including an anticancer effect, but low water solubility limits its clinical application. The aim of this study was to develop a lecithin-based mixed polymeric micelle (LMPM) delivery system to improve the solubility and bioavailability of Que. Th...
Autores principales: | Chen, Ling-Chun, Chen, Ying-Chen, Su, Chia-Yu, Hong, Chung-Shu, Ho, Hsiu-O, Sheu, Ming-Thau |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841422/ https://www.ncbi.nlm.nih.gov/pubmed/27143878 http://dx.doi.org/10.2147/IJN.S103681 |
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