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Direct Observation of α-Synuclein Amyloid Aggregates in Endocytic Vesicles of Neuroblastoma Cells

Aggregation of α-synuclein has been linked to both familial and sporadic Parkinson’s disease. Recent studies suggest that α-synuclein aggregates may spread from cell to cell and raise questions about the propagation of neurodegeneration. While continuous progress has been made characterizing α-synuc...

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Detalles Bibliográficos
Autores principales: Apetri, Mihaela M., Harkes, Rolf, Subramaniam, Vinod, Canters, Gerard W., Schmidt, Thomas, Aartsma, Thijs J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841506/
https://www.ncbi.nlm.nih.gov/pubmed/27105068
http://dx.doi.org/10.1371/journal.pone.0153020