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Early Combination Antiretroviral Therapy Limits Exposure to HIV-1 Replication and Cell-Associated HIV-1 DNA Levels in Infants

The primary aim of this study was to measure HIV-1 persistence following combination antiretroviral therapy (cART) in infants and children. Peripheral blood mononuclear cell (PBMC) HIV-1 DNA was quantified prior to and after 1 year of cART in 30 children, stratified by time of initiation (early, age...

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Detalles Bibliográficos
Autores principales: McManus, Margaret, Mick, Eric, Hudson, Richard, Mofenson, Lynne M., Sullivan, John L., Somasundaran, Mohan, Luzuriaga, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841514/
https://www.ncbi.nlm.nih.gov/pubmed/27104621
http://dx.doi.org/10.1371/journal.pone.0154391