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Listeriolysin O Membrane Damaging Activity Involves Arc Formation and Lineaction -- Implication for Listeria monocytogenes Escape from Phagocytic Vacuole

Listeriolysin-O (LLO) plays a crucial role during infection by Listeria monocytogenes. It enables escape of bacteria from phagocytic vacuole, which is the basis for its spread to other cells and tissues. It is not clear how LLO acts at phagosomal membranes to allow bacterial escape. The mechanism of...

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Detalles Bibliográficos
Autores principales: Ruan, Yi, Rezelj, Saša, Bedina Zavec, Apolonija, Anderluh, Gregor, Scheuring, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841516/
https://www.ncbi.nlm.nih.gov/pubmed/27104344
http://dx.doi.org/10.1371/journal.ppat.1005597