The Clinical Significance of Interleukin–1 Receptor Antagonist +2018 Polymorphism in Rheumatoid Arthritis

OBJECTIVE: Interleukin-1 receptor antagonist (IL-1Ra) acts as an inhibitor of IL-1; which is one of the culprit cytokines in rheumatoid arthritis (RA). Although +2018 polymorphism of IL-1Ra has been implicated in the pathogenesis of RA, its importance remains poorly understood. Hence, the purpose of...

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Detalles Bibliográficos
Autores principales: Ismail, Endom, Nofal, Omimah Khaled Jaber, Sakthiswary, Rajalingham, Shaharir, Syahrul Sazliyana, Sridharan, Radhika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841519/
https://www.ncbi.nlm.nih.gov/pubmed/27105431
http://dx.doi.org/10.1371/journal.pone.0153752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841519/
https://www.ncbi.nlm.nih.gov/pubmed/27105431
http://dx.doi.org/10.1371/journal.pone.0153752

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