SRPK1 and Akt Protein Kinases Phosphorylate the RS Domain of Lamin B Receptor with Distinct Specificity: A Combined Biochemical and In Silico Approach

Activated Akt has been previously implicated in acting on RS domain-containing proteins. However, it has been questioned whether its action is direct or it is mediated by co-existing SR kinase activity. To address this issue we studied in detail the phosphorylation of Lamin B Receptor (LBR) by Akt....

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Detalles Bibliográficos
Autores principales: Voukkalis, Nikolaos, Koutroumani, Maria, Zarkadas, Christoforos, Nikolakaki, Eleni, Vlassi, Metaxia, Giannakouros, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841541/
https://www.ncbi.nlm.nih.gov/pubmed/27105349
http://dx.doi.org/10.1371/journal.pone.0154198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841541/
https://www.ncbi.nlm.nih.gov/pubmed/27105349
http://dx.doi.org/10.1371/journal.pone.0154198

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