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SRPK1 and Akt Protein Kinases Phosphorylate the RS Domain of Lamin B Receptor with Distinct Specificity: A Combined Biochemical and In Silico Approach
Activated Akt has been previously implicated in acting on RS domain-containing proteins. However, it has been questioned whether its action is direct or it is mediated by co-existing SR kinase activity. To address this issue we studied in detail the phosphorylation of Lamin B Receptor (LBR) by Akt....
Autores principales: | Voukkalis, Nikolaos, Koutroumani, Maria, Zarkadas, Christoforos, Nikolakaki, Eleni, Vlassi, Metaxia, Giannakouros, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841541/ https://www.ncbi.nlm.nih.gov/pubmed/27105349 http://dx.doi.org/10.1371/journal.pone.0154198 |
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