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The Role of Genome Accessibility in Transcription Factor Binding in Bacteria
ChIP-seq enables genome-scale identification of regulatory regions that govern gene expression. However, the biological insights generated from ChIP-seq analysis have been limited to predictions of binding sites and cooperative interactions. Furthermore, ChIP-seq data often poorly correlate with in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841574/ https://www.ncbi.nlm.nih.gov/pubmed/27104615 http://dx.doi.org/10.1371/journal.pcbi.1004891 |