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GPR142 Agonists Stimulate Glucose-Dependent Insulin Secretion via Gq-Dependent Signaling
GPR142 is an islet-enriched G protein-coupled receptor that has been investigated as a novel therapeutic target for the treatment of type 2 diabetes by virtue of its insulin secretagogue activity. However, the signaling pathways downstream of GPR142 and whether its stimulation of insulin release is...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841597/ https://www.ncbi.nlm.nih.gov/pubmed/27104960 http://dx.doi.org/10.1371/journal.pone.0154452 |