Reconstruction of Cell Surface Densities of Ion Pumps, Exchangers, and Channels from mRNA Expression, Conductance Kinetics, Whole-Cell Calcium, and Current-Clamp Voltage Recordings, with an Application to Human Uterine Smooth Muscle Cells

Uterine smooth muscle cells remain quiescent throughout most of gestation, only generating spontaneous action potentials immediately prior to, and during, labor. This study presents a method that combines transcriptomics with biophysical recordings to characterise the conductance repertoire of these...

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Detalles Bibliográficos
Autores principales: Atia, Jolene, McCloskey, Conor, Shmygol, Anatoly S., Rand, David A., van den Berg, Hugo A., Blanks, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841602/
https://www.ncbi.nlm.nih.gov/pubmed/27105427
http://dx.doi.org/10.1371/journal.pcbi.1004828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841602/
https://www.ncbi.nlm.nih.gov/pubmed/27105427
http://dx.doi.org/10.1371/journal.pcbi.1004828

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