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Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism

Cancer-associated fibroblasts (CAFs) are a major cellular component of tumor microenvironment in most solid cancers. Altered cellular metabolism is a hallmark of cancer, and much of the published literature has focused on neoplastic cell-autonomous processes for these adaptations. We demonstrate tha...

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Detalles Bibliográficos
Autores principales: Zhao, Hongyun, Yang, Lifeng, Baddour, Joelle, Achreja, Abhinav, Bernard, Vincent, Moss, Tyler, Marini, Juan C, Tudawe, Thavisha, Seviour, Elena G, San Lucas, F Anthony, Alvarez, Hector, Gupta, Sonal, Maiti, Sourindra N, Cooper, Laurence, Peehl, Donna, Ram, Prahlad T, Maitra, Anirban, Nagrath, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841778/
https://www.ncbi.nlm.nih.gov/pubmed/26920219
http://dx.doi.org/10.7554/eLife.10250