Synthesis and pharmacological evaluation of mono-arylimidamides as antileishmanial agents

Arylimidamide (AIA) compounds containing two pyridylimidamide terminal groups (bis-AIAs) possess outstanding in vitro antileishmanial activity, and the frontrunner bis-AIA DB766 (2,5-bis[2-(2-isopropoxy)-4-(2-pyridylimino)aminophenyl]furan) is active in visceral leishmaniasis models when given orall...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaohua, Farahat, Abdelbasset A., Mattamana, Meena, Joice, April, Pandharkar, Trupti, Holt, Elizabeth, Banerjee, Moloy, Gragg, Jamie L., Hu, Laixing, Kumar, Arvind, Yang, Sihyung, Wang, Michael Zhuo, Boykin, David W., Werbovetz, Karl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841789/
https://www.ncbi.nlm.nih.gov/pubmed/27048943
http://dx.doi.org/10.1016/j.bmcl.2016.03.082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841789/
https://www.ncbi.nlm.nih.gov/pubmed/27048943
http://dx.doi.org/10.1016/j.bmcl.2016.03.082

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