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Phenylbutyrate—a pan-HDAC inhibitor—suppresses proliferation of glioblastoma LN-229 cell line

Phenylbutyrate (PBA) is a histone deacetylase inhibitor known for inducing differentiation, cell cycle arrest, and apoptosis in various cancer cells. However, the effects of PBA seem to be very cell-type-specific and sometimes limited exclusively to a particular cell line. Here, we provided novel in...

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Detalles Bibliográficos
Autores principales: Kusaczuk, Magdalena, Krętowski, Rafał, Bartoszewicz, Marek, Cechowska-Pasko, Marzanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841856/
https://www.ncbi.nlm.nih.gov/pubmed/26260271
http://dx.doi.org/10.1007/s13277-015-3781-8