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Basal metabolic state governs AIF-dependent growth support in pancreatic cancer cells

BACKGROUND: Apoptosis-inducing factor (AIF), named for its involvement in cell death pathways, is a mitochondrial protein that regulates metabolic homeostasis. In addition to supporting the survival of healthy cells, AIF also plays a contributory role to the development of cancer through its enzymat...

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Detalles Bibliográficos
Autores principales: Scott, Andrew J., Wilkinson, Amanda S., Wilkinson, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841948/
https://www.ncbi.nlm.nih.gov/pubmed/27108222
http://dx.doi.org/10.1186/s12885-016-2320-3