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Basal metabolic state governs AIF-dependent growth support in pancreatic cancer cells
BACKGROUND: Apoptosis-inducing factor (AIF), named for its involvement in cell death pathways, is a mitochondrial protein that regulates metabolic homeostasis. In addition to supporting the survival of healthy cells, AIF also plays a contributory role to the development of cancer through its enzymat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841948/ https://www.ncbi.nlm.nih.gov/pubmed/27108222 http://dx.doi.org/10.1186/s12885-016-2320-3 |