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Basal metabolic state governs AIF-dependent growth support in pancreatic cancer cells

BACKGROUND: Apoptosis-inducing factor (AIF), named for its involvement in cell death pathways, is a mitochondrial protein that regulates metabolic homeostasis. In addition to supporting the survival of healthy cells, AIF also plays a contributory role to the development of cancer through its enzymat...

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Detalles Bibliográficos
Autores principales:	Scott, Andrew J., Wilkinson, Amanda S., Wilkinson, John C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841948/ https://www.ncbi.nlm.nih.gov/pubmed/27108222 http://dx.doi.org/10.1186/s12885-016-2320-3

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