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Longitudinal genome-wide methylation study of Roux-en-Y gastric bypass patients reveals novel CpG sites associated with essential hypertension

BACKGROUND: Essential hypertension is a significant risk factor for cardiovascular diseases. Emerging research suggests a role of DNA methylation in blood pressure physiology. We aimed to investigate epigenetic associations of promoter related CpG sites to essential hypertension in a genome-wide met...

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Detalles Bibliográficos
Autores principales: Boström, Adrian E., Mwinyi, Jessica, Voisin, Sarah, Wu, Wenting, Schultes, Bernd, Zhang, Kang, Schiöth, Helgi B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841955/
https://www.ncbi.nlm.nih.gov/pubmed/27105587
http://dx.doi.org/10.1186/s12920-016-0180-y