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Salivary miRNA profiles identify children with autism spectrum disorder, correlate with adaptive behavior, and implicate ASD candidate genes involved in neurodevelopment

BACKGROUND: Autism spectrum disorder (ASD) is a common neurodevelopmental disorder that lacks adequate screening tools, often delaying diagnosis and therapeutic interventions. Despite a substantial genetic component, no single gene variant accounts for >1 % of ASD incidence. Epigenetic mechanisms...

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Detalles Bibliográficos
Autores principales: Hicks, Steven D., Ignacio, Cherry, Gentile, Karen, Middleton, Frank A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841962/
https://www.ncbi.nlm.nih.gov/pubmed/27105825
http://dx.doi.org/10.1186/s12887-016-0586-x