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RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

The DNA replication machinery invariably encounters obstacles that slow replication fork progression, and threaten to prevent complete replication and faithful segregation of sister chromatids. The resulting replication stress activates ATR, the major kinase involved in resolving impaired DNA replic...

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Detalles Bibliográficos
Autores principales: Kanu, Nnennaya, Zhang, Tianyi, Burrell, Rebecca A., Chakraborty, Atanu, Cronshaw, Janet, Da Costa, Clive, Grönroos, Eva, Pemberton, Helen N., Anderton, Emma, Gonzalez, Laure, Sabbioneda, Simone, Ulrich, Helle D., Swanton, Charles, Behrens, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842010/
https://www.ncbi.nlm.nih.gov/pubmed/26549024
http://dx.doi.org/10.1038/onc.2015.427